Power Rankings based on how they spiro, from least to most powerful:

Drink it with water

Swallow it dry

Chew it

Sublingually

Grind it up into a powder and snort it

Grind a whole bunch of spiro pills into a mountain of powder and then smear your face all over it like you're in Scarface

yeehaw

the forbidden final tier, gore, extremely dont do this 

Powdering a mass of them and then turning that powder into a knife like you're that youtube guy which you then use to slice off your nuts entirely

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the forbidden final tier, gore, extremely dont do this 

@fluxom_alt world's hardest spironolactone knife, strong enough to cut any cucumber but so fragile as to shatter when held except with the gentle touch of a transbian

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